Sulisobenzone
The question

Is Sulisobenzone safe in sunscreen?

CautionSunscreen

A water-soluble benzophenone UV filter and UV-absorber that is a recognized contact allergen and for which US regulators have requested more safety data.

What the research flags

  • In North American Contact Dermatitis Group patch testing of 19,618 patients (2013 to 2020), benzophenone-4 (sulisobenzone) produced positive reactions in 1.6 percent, of which 65.8 percent were judged currently clinically relevant, with sources including personal-care products and sunscreens (Warshaw 2023, PMID 36917534)
  • Benzophenone organic UV filters as a class have caused allergic and photoallergic contact dermatitis (Ekstein 2023, PMID 36279254)

Regulatory
IARC Class: NL

Other sunscreen ingredients on file

Sources & references

  1. [1]
    Peer-reviewedPubMed / NCBI — pubmed.ncbi.nlm.nih.gov · ref 36917534
  2. [2]
    Peer-reviewedPubMed / NCBI — pubmed.ncbi.nlm.nih.gov · ref 36279254

Research disclaimer: Ratings reflect peer-reviewed research and regulatory assessments available at the time of publication, not the dose or formulation of any specific sunscreen product. This is not medical advice.