Specimen No. 0189
AvoidSyntheticfood synthetic preservatives
Propyl Gallate
E310
Master DB rating: Avoid. Listed for: Vegetable oils, meat products, microwave popcorn
medium confidence
Researched July 7, 2026Specimen 0189Propyl Gallate
Concerns
- In vitro assays found propyl gallate binds and inhibits human thyroid peroxidase (TPO) at concentrations close to estimated real-world dietary intake levels (Punt et al. 2020)
- Separate in vitro studies found estrogenic and anti-estrogenic activity in breast cancer cell lines (Pop et al. 2018), though physiologically based modeling suggests estrogenic effects are unlikely at typical dietary exposure
Regulatory flags
- ⚑IARC Class: NL
- ⚑EDC Status: Suspected (thyroid peroxidase inhibition in vitro)
- ⚑Regulatory: US: FDA permitted; EU: restricted
- ⚑Evidence Grade: C
Commonly found in
Vegetable oils, meat products, microwave popcorn
Sources & references
Last researched: July 7, 2026
Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.
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