The Lab
Specimen No. 0038
CautionSyntheticemulsifiersurfactant

Polysorbate 20 / 60 / 80

polysorbate 20 · polysorbate 60 · polysorbate 80

PEG-derived emulsifiers that stabilize oil-water mixtures. Can be contaminated with 1,4-dioxane and ethylene oxide; may also disrupt gut microbiome when consumed.

medium confidence
Researched April 18, 2026

Concerns

  • Potential 1,4-dioxane and ethylene oxide contamination (manufacturing byproducts)
  • Polysorbate 80 linked to gut microbiome disruption and low-grade inflammation in animal studies [inference]
  • Enhances skin penetration
  • PEG-derived — petroleum origin

Regulatory flags

  • Ethoxylation process can introduce 1,4-dioxane (IARC Group 2B) as impurity

Commonly found in

MoisturizerSerumSunscreenVaccine adjuvantsFood emulsification

Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.

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