Specimen No. 0038
CautionSyntheticemulsifiersurfactant
Polysorbate 20 / 60 / 80
polysorbate 20 · polysorbate 60 · polysorbate 80
PEG-derived emulsifiers that stabilize oil-water mixtures. Can be contaminated with 1,4-dioxane and ethylene oxide; may also disrupt gut microbiome when consumed.
medium confidence
Researched April 18, 2026Specimen 0038Polysorbate 20 / 60 / 80
Concerns
- Potential 1,4-dioxane and ethylene oxide contamination (manufacturing byproducts)
- Polysorbate 80 linked to gut microbiome disruption and low-grade inflammation in animal studies [inference]
- Enhances skin penetration
- PEG-derived — petroleum origin
Regulatory flags
- ⚑Ethoxylation process can introduce 1,4-dioxane (IARC Group 2B) as impurity
Commonly found in
MoisturizerSerumSunscreenVaccine adjuvantsFood emulsification
Sources & references
Last researched: April 18, 2026
Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.
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