Specimen No. 0219
CautionDerivedfood additivethickener
Maltodextrin
CAS 9050-36-6 · E1400 · malto-dextrin · modified food starch (maltodextrin)
Refined starch-derived polysaccharide used as a filler, thickener and carrier. It is digested to glucose and produces a high glycemic response; mouse and in-vitro studies link it to gut-barrier and microbiome effects relevant to inflammatory bowel disease susceptibility.
medium confidence
Researched July 7, 2026Specimen 0219Maltodextrin
Concerns
- In-vitro and cell studies show maltodextrin enhances biofilm formation and epithelial adhesion of Crohn's-disease-associated adherent-invasive E. coli (Nickerson & McDonald 2012)
- In mice, a maltodextrin-enriched diet drove endoplasmic-reticulum-stress-mediated depletion of the protective intestinal mucus layer and worsened experimental colitis (Laudisi et al. 2018)
Regulatory flags
- ⚑IARC Class: NL
- ⚑EDC Status: None
- ⚑Regulatory: US: GRAS; EU: permitted
- ⚑Evidence Grade: B (animal / in-vitro)
Commonly found in
Protein powdersSaucesInstant foodsSugar substitutesSnack seasonings
Sources & references
Last researched: July 7, 2026
Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.
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