Specimen No. 0173
CautionSyntheticcolorantdye

Blue 1 / Brilliant Blue FCF

blue 1 · fd&c blue 1 · e133

A synthetic non-azo colorant approved by the FDA and EFSA. EFSA found no established carcinogenicity or genotoxicity but notes moderate risk of ADI exceedance in children eating high-dye diets. Some preclinical studies raise neurotoxicity concerns. Rare allergic reactions and hypersensitivity responses have been documented.

medium confidence
Researched April 18, 2026
Blue 1 / Brilliant Blue FCF molecular structure
Specimen 0173Blue 1 / Brilliant Blue FCF

Concerns

  • Neurotoxicity potential in preclinical studies — mechanism not fully characterized [Inference]
  • ADI exceedance risk in children with high-dye diets (EFSA)
  • Rare allergic reactions and hypersensitivity reported
  • Linked to hyperactivity in some behavioral studies

Regulatory flags

  • Not approved in EU as a food dye

Commonly found in

CandyBeveragesBaked goodsFrostingsConfectioneryIce cream

Last researched: April 18, 2026

Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.

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