Specimen No. 0167
CautionSyntheticsweetenerfood additive
Sucralose (Splenda)
sucralose · e955 · splenda
A chlorinated artificial sweetener approximately 600× sweeter than sugar. FDA and EFSA-approved with an ADI of 15 mg/kg body weight. The WHO issued a cautionary advisory in 2023 suggesting long-term consumption may have health implications not yet fully characterized. Short-term human studies show no significant effects on blood glucose or gut bacteria.
medium confidence
Researched April 18, 2026Specimen 0167Sucralose (Splenda)
Concerns
- WHO 2023 advisory raises questions about long-term health implications
- Some studies suggest possible gut microbiome effects at high doses [Inference]
- Contains chlorine atoms — though not equivalent to chlorinated solvents
- Long-term safety data still accumulating
Regulatory flags
- ⚑WHO (2023): non-sugar sweeteners not recommended for long-term use
Commonly found in
Diet sodasSugar-free candyLow-calorie foodsProtein barsArtificially sweetened yogurt
Sources & references
Last researched: April 18, 2026
Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.
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