Specimen No. 0126
CautionSyntheticsunscreenuv filter

Octisalate (Octyl Salicylate)

octisalate · octyl salicylate · 2-ethylhexyl salicylate

An oil-soluble UVB filter approved up to 5% in US sunscreens. Systemic absorption exceeds FDA safety thresholds and the EU has flagged reproductive and developmental concerns in regulatory assessments. Does not protect against UVA radiation.

medium confidence
Researched April 18, 2026
Octisalate (Octyl Salicylate) molecular structure
Specimen 0126Octisalate (Octyl Salicylate)

Concerns

  • Systemic absorption exceeds FDA threshold (0.5 ng/mL) after application [Inference]
  • EU assessment flagged potential reproductive and developmental toxicity [Inference]
  • No UVA protection — must be paired with UVA filter
  • Not reef-safe — contributes to coral bleaching

Regulatory flags

  • FDA proposed non-GRASE status (2019 — further safety testing required)

Commonly found in

Chemical sunscreenSPF moisturizersBody sunscreenSpray sunscreen

Safer swaps we'd look at

Thinksport

Thinksport SPF 50+

94/100

The cleanest mineral sunscreen we've found. Zero hormone disruptors.

Why it's cleaner

No flagged ingredients in our current review; key ingredients include Zinc oxide 20%, Sunflower seed oil, Shea butter.

Zinc oxide 20%Sunflower seed oilShea butter
View product

Pipette

Pipette Mineral SPF 50

89/100

Sheer mineral SPF designed for sensitive skin.

Why it's cleaner

No flagged ingredients in our current review; key ingredients include Zinc oxide 20%, Squalane, Bisabolol.

Zinc oxide 20%SqualaneBisabolol
View product

Last researched: April 18, 2026

Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.

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