AvoidSyntheticfood artificial dyes

Caramel Color IV

E150d

An ammonia-sulfite process caramel coloring used in colas, soy sauce, and baked goods. It can contain 4-methylimidazole (4-MEI), which IARC lists as a Group 2B possible carcinogen.

low confidence
Researched July 7, 2026
  • Contains 4-MEI, which IARC lists as a Group 2B possible carcinogen; listed under California Prop 65; the EU sets exposure limits
  • IARC Class: Gr2B (via 4-MEI content)
  • EDC Status: None
  • Regulatory: US: FDA GRAS; EU: exposure limits; CA: Prop 65
  • Evidence Grade: B
Colas, soy sauce, baked goods

Research disclaimer: This rating is based on available peer-reviewed research and regulatory assessments at the time of publication. It is not medical advice. Consult a qualified professional for personal health or skin concerns.

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LabelCleared verdict badge: Caramel Color IV — Avoid
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